Possibility of use and effectiveness of oral hypoglyctic drugs in gestational diabetes mellitus: a literature review
نویسندگان
چکیده
Gestational diabetes mellitus (GDM) is a serious and frequent concern in pregnancy. Worldwide, the prevalence of GDM ranges from 8 to 20%. In 5% cases, this pathology accompanied by complications such as diabetic fetopathy, preeclampsia, neonatal hypoglycemia, hyperbilirubinemia. Modern national foreign guidelines for detecting hyperglycemia during pregnancy diagnosing recommend lifestyle changes adherence carbohydrate-restricted diet initial therapy. absence positive dynamics against background non-drug therapy, Russian Federation recommends only use insulin.
 A number consider oral hypoglycemic agents (metformin and/or glibenclamide) an alternative injectable drugs. review, we compared efficacy safety metformin glibenclamide treating GDM. Metformin are reliable safe correcting level blood glucose pregnant women, but optimal therapeutic strategy includes their combined or with insulin.
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ژورنال
عنوان ژورنال: Arhiv akušerstva i ginekologii im. V.F. Snegireva
سال: 2021
ISSN: ['2313-8726', '2687-1386']
DOI: https://doi.org/10.17816/2313-8726-2021-8-4-207-212